Development of HPLC solvent waste reduction instrument

Multi-award-winning provider

Based in Waterford, Antech are a multi-award-winning provider of handheld spectrometers, analysers and Process Analytical Technology (PAT) solutions. Antech serve a wide variety of sectors including pharmaceuticals, biopharma, nutraceutical,
chemical companies, academia, food manufacturers and the recycling industry.

The company is especially focused on meeting the regulatory challenges required within GMP (Good Manufacturing Practice) facilities by providing processes, procedures, documentation and expertise that exceed the industry needs.

Antech have developed a device which can be installed on High Performance Liquid Chromatography (HPLC) systems which dramatically reduces the amount of organic solvent waste generated during GMP laboratory analysis. Antech needed to test and refine the device in a real laboratory environment to confirm the effectiveness of the device and show that it could robustly perform under typical analysis conditions.

Test and refine in a laboratory environment

PMBRC installed the device on their instrumentation and challenged the performance of the device under a series of analysis runs. The data generated was shared with Antech who then refined the software and hardware to improve its practical
functionality. In addition, parameters for analytical test methods were optimised to enable future device IQOQPQ (Installation, Operational and Performance Qualification) tests.

These IQOQPQ protocols are essential to ensure that devices will be delivered, installed and function correctly for use within the highly regulated Life Science markets.

Ultimately this project was able to confirm the effectiveness and robustness of the Antech technology to reduce solvent waste during typical laboratory analysis.


Irish Company


Innovation Voucher


analysis report

” The work completed by PMBRC provided a local, highly professional and industry-aware partner for Antech to verify our product functionality within a live laboratory environment. During early meetings it became evident that the PMBRC team totally understood our product proposition and are fully aware of the regulatory challenges that we wish to overcome for our target market. Timely data generation and reporting helped us to meet our product development roadmap and has ensured Antech can move towards the latter stages of our product commercialisation.”

Dermot Harrington, Managing Director, Antech Solutions Ltd.

Antech & PMBRC Technology Gateway partnership

The project allowed Antech to confirm the performance of their device in a real analytical laboratory and refine its functionality based on the results. This in turn has enabled Antech to offer this product to potential customers.

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