Optimising a Delivery System Through Clinically Relevant Testing
Clinically relevant environment
Paradox Medical partnered with MET Technology Gateway at Atlantic Technological University (ATU) and LifeTec Group to test its delivery system in a clinically relevant environment. Testing with real hearts in MET’s imaging suite revealed challenges that bench work had not identified, informing subsequent optimisation of the delivery system. Procedure videos and fluoroscopy recordings also provided evidence of development progress for investors and a shared reference for the company’s engineers and clinical collaborators.
Paradox Medical needed to understand how its delivery system would behave in real heart anatomy. Despite extensive bench testing, the team encountered previously unforeseen challenges when testing in a more lifelike environment. Identifying these issues was important for guiding further engineering development. The company also needed clear evidence of progress for investor discussions and a way for its engineers and clinical collaborators to review the same observations, understand device behaviour and plan the next round of R&D testing.
Specialist expertise
MET combined its imaging suite and specialist expertise with LifeTec’s animal heart model to support clinically relevant testing of Paradox Medical’s delivery system.
- Clinically Relevant Testing: The LifeTec study used real hearts in MET’s imaging suite, allowing Paradox Medical to assess its delivery system in a lifelike setting without the complexities associated with a live animal study.
- Expert Support: Paradox Medical identified the imaging suite and Florian’s support as particularly valuable. MET’s facilities and technical expertise supported testing with the LifeTec heart model.
- Procedure Recording and Fluoroscopy: Recordings captured the procedure for later review, supporting discussions with clinicians, technical assessment and communication of development progress to investors.
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Irish Company
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Direct funded project
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Clinical testing environment
“The testing we conducted at MET represented a highly significant step towards the development of our cardiac implant, and represented the single biggest milestone to date”
Willie Costelloe, CEO, Paradox Medical
Paradox Medical & MET Technology Gateway partnership
The collaboration between Paradox Medical, MET Technology Gateway and LifeTec Group helped uncover delivery-system challenges that bench testing had not revealed. Paradox used those findings to guide optimisation, while the procedure videos and fluoroscopy supported technical communication and investor engagement. Access to MET’s imaging suite and specialist expertise provided a practical setting for clinically relevant testing and a basis for planning further development work with MET and LifeTec.